Syphilis is most commonly spread through sexual activity. Syphilis has been known as " the great imitator" as it may cause symptoms similar to many other diseases. In tertiary syphilis, there are gummas (soft, non-cancerous growths), neurological problems, or heart symptoms. In latent syphilis, which can last for years, there are few or no symptoms. There may also be sores in the mouth or vagina. In secondary syphilis, a diffuse rash occurs, which frequently involves the palms of the hands and soles of the feet. ![]() ![]() The primary stage classically presents with a single chancre (a firm, painless, non-itchy skin ulceration usually between 1 cm and 2 cm in diameter) though there may be multiple sores. The signs and symptoms of syphilis vary depending in which of the four stages it presents (primary, secondary, latent, and tertiary). Syphilis ( / ˈ s ɪ f ə l ɪ s/) is a sexually transmitted infection caused by the bacterium Treponema pallidum subspecies pallidum. Treponema pallidum usually spread by sex īlood tests, dark field microscopy of infected fluid Ĭondoms, Long-term monogamous relationships ![]() Electron micrograph of Treponema pallidum
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